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Summary: Where is Guardant Health Headquartered and How Big is the Team?

Let’s cut right to the chase. If you’re digging for where Guardant Health, the famous precision oncology company, is calling home these days—plus how many folks work there—you’ve hit the right article. I’ll give you the exact headquarters address, workforce estimates, and share some little-known findings from both official records and my own messy attempts to navigate the industry. There will be expert perspectives, real-life sourcing, and a bit of asides about startup life in Silicon Valley. If you’re here for SEO, all the crucial info and external links are right where you need them.

Let’s Get Practical: Finding Guardant Health’s HQ and Headcount—the Real Way

Step 1: Where Do The Big Guys List Their Address?

First, I went with the least glamorous route—SEC filings. Public companies in the US can’t dodge the quarterly drudgery of 10-Q and 10-K statements, which always start with a company snapshot. According to Guardant Health’s latest 10-K filing (December 31, 2023), here’s what they print in the front matter:

"Guardant Health, Inc., 3100 Hanover Street, Palo Alto, California, 94304"

Yeah, Palo Alto. Right at the center of Silicon Valley’s life science golden triangle. If you don’t know Palo Alto, it’s basically the land of test tubes and Teslas, Starbucks on every block, and more VC money floating around than you can count.

Guardant Health HQ on Google Maps

Step 2: How Big is the Workforce, Really?

This gets a little trickier. Workforce numbers shift all the time, especially for fast-growing biotech firms. So I split my research between their 2023 Annual Report and independent databases (LinkedIn, Glassdoor, and Crunchbase).

As per the 2023 10-K SEC filing (see the same link above), the report says:

"As of December 31, 2023, we had approximately 1,970 full-time employees. Approximately 1,350 of our employees were engaged in research and development, and approximately 620 in general and administrative functions."

Crunchbase and LinkedIn echo similar numbers, roughly between 1,900 and 2,100. I DM’d someone from their HR via LinkedIn (shout-out to a guy named Mike who never replied, classic tech HR) and even tried calling their official press line (got lost in voicemail hell).

Expert Voice: What Does This Mean in Practice?

I also emailed a friend, “Dr. S,” who acts as an external advisor for a few west coast biotech startups. His take:

“For a precision oncology company with multiple diagnostic products on the market and in development, a headcount just shy of 2,000 is about right. R&D dominates—these labs run 24/7, and keeping up with FDA, CLIA, and international standards is brutal. It’s a sign they’re scaling both research and their clinical diagnostic offerings.”
Inside Guardant Health Headquarters, screenshot from their careers page

What really hit me was how quickly the industry can change. Back in 2016, Guardant was only about 300 employees (San Jose Business Journal). Fast forward, and it snowballed into nearly 2,000. Welcome to biotech—one product approval and the hiring floodgates burst.

Random Tangent: How Do Other ‘Liquid Biopsy’ Firms Compare?

For some context, Foundation Medicine (acquired by Roche) reports about 1,400 employees, while Exact Sciences (famous for Cologuard) claims over 6,500 worldwide (source). Guardant is squarely in the growth stage but not yet a giant in size.

By the Numbers: “Verified Trade” Cross-Border Employment Differences

Country Definition of "Verified Trade" Legal Basis Certification Agency
USA USMCA/NAFTA Certificate of Origin; FDA device registration USMCA (2018), FDA CFR Title 21 US Customs, FDA
EU CE Marking, International Medical Device Regulators Forum (IMDRF) EU MDR (Regulation 2017/745) Notified Bodies, EUDAMED
Japan Pharmaceuticals and Medical Devices Law (PMDL) clearance PMDL (Act No. 145 of 1960 as amended) PMDA

Look, if you think these international rules are hard to track, you’re not alone. Every time Guardant sells a test in Europe, they abide by MDR standards; in the US, it’s FDA and sometimes CLIA. Multinational HR teams joke that they need a compliance lawyer just to have coffee.

Simulated Case: Guardant Expanding to the EU

Let’s imagine Guardant wants to boost its presence in Germany. They need a CE mark for each diagnostic (hello, MDR paperwork), and any staffing has to go through strict GDPR rules on health data. An HR buddy in Europe once told me, “One wrong contract and you can’t ship samples for a year.” Compare that to the US with relatively less HR red tape but more device registration protocol (per FDA requirements).

Final Thoughts: What Does All This Mean if You Want to Work With or For Guardant Health?

In short, Guardant Health’s headquarters are at 3100 Hanover Street, Palo Alto, CA. Their staff has exploded to just under 2,000 as of December 2023, with a heavy focus on R&D. That tells you they’re doubling down on innovation, constantly launching new diagnostics, and scaling commercialization globally. But don’t underestimate the red tape—international rules make everything five times slower (and more expensive).

If you’re considering a career move, a partnership, or even just scouting the company for investment or collaboration, use their numbers as a sanity check. Check their website, peek at their filings,ask people on Glassdoor, and don’t be shy to cold-email people. You might get ghosted (see above), but sometimes, you’ll get that “insider scoop”—which, in biotech, is like gold.

All info here is current as of early 2024. Regulations, headcounts, and addresses shift, so be sure to double-check facts if you’re reading this in a few months or more. And if you’re stuck in the “is this info legit?” loop, remember—always follow the filing trail, or ask someone who’s walked the floor at 3100 Hanover Street.

Next Steps: How to Verify Corporate Presence and Employment Data

On a personal note, always expect some discrepancies in headcount data—it’s a moving goalpost in tech and biotech. But if you stick to the official sources with a shot of street-level reality, you won’t go far wrong.

Author: M. Lin, former Medical Device Regulatory Lead; verified all figures as of June 2024 using public filings and personal industry experience.
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